Figure 1: The 2001 Bethesda system
| Specimen adequacy | ||||
|
Satisfactory for evaluation (note the presence/absence of endocervical/transformation zone component) | |||
|
Unsatisfactory for evaluation.............(specify reason) | |||
| General categorisation (Optional) | ||||
|
Negative for intraepithelial lesion or malignancy | |||
|
Epithelial cell abnormality | |||
|
Other | |||
| Interpretation/result | ||||
|
Negative for Intraepithelial Lesion or Malignancy | |||
| - | Organisms such as trichomonas vaginalis, candida species | |||
| - | Other non-neoplastic findings (optional) such as reactive cellular changes associated with inflammation, radiation or IUCD | |||
| - | Glandular cells status posthysterectomy | |||
| - | Atrophyn | |||
|
Epithelial Cell Abnormality | |||
| Squamous cells | ||||
 |
Atypical squamous cells (ASC) | |||
 |
Of undetermined significance (ASC-US) | |||
|
Cannot exclude HSIL (ASC-H) | |||
|
Low-grade squamous intraepithelial lesion (LSIL) | |||
|
Encompassing: human papillomavirus (HPV)/mild dysplasia/cervical intraepithelial neoplasia (CIN) 1 | |||
| High-grade squamous intraepithelial lesion (HSIL) | ||||
|
Encompassing: moderate and severe dysplasia, carcinoma in situ; CIN 2 and CIN 3 | |||
|
Squamous cell carcinoma | |||
| - | Glandular cell | |||
|
Atypical glandular cells (AGC) | |||
|
Atypical glandular cells, favour neoplastic (specify endocervical or not otherwise specified) | |||
|
Endocervical adenocarcinoma in situ (AIS) | |||
|
Adenocarcinoma | |||
|
Encompassing: moderate and severe dysplasia, carcinoma in situ; CIN 2 and CIN 3 | |||
| - | Other (e.g. endometrial cells in a
woman  40 years
of age) |
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