|
|
Framingham cohort study |
|
Chinese multi-provincial cohort study (CMCS) |
Setting |
|
Framingham, Massachusetts 1971 to 1983 (12
years follow up) |
|
11 provinces in China 1992 to 2002 (10 years
follow up) |
Participants |
|
5,215 US White men and women aged 30-74 |
|
30,121 Chinese men and women aged 35-64 |
Risk factors measured |
|
BP, Smoking, DM, TC, HDL |
|
BP, Smoking, DM, TC, HDL BMI, Physical activity |
Outcome measure |
|
CHD events (acute myocardial infarction, sudden
death, other coronary deaths) |
|
CHD events (acute myocardial infarction, sudden
death, other coronary deaths) |
Hard CHD events for 10 years of follow-up |
|
195
(71.4%) |
|
78
(28.6%) |
|
273
(100%) |
|
137
(70.6%) |
|
54
(28.3%) |
|
191
(100%) |
Person-years of follow-up |
|
22,471 |
|
26,647 |
|
49,118 |
|
94,655 |
|
85,127 |
|
179,782 |
Events per 100,000 person-years |
|
868 |
|
293 |
|
556 |
|
145 |
|
64 |
|
106 |
10-year event rate without |
|
8.0% |
|
2.8% |
|
- |
|
1.5% |
|
0.6% |
|
- |