Figure 1: Average number of different antihypertensive drugs needed to achieve blood pressure goals in major hypertension trials. (UKPDS, United Kingdom Prospective Diabetes Study; ABCD, Appropriate Blood Pressure Control in Diabetes; MDRD, Modification of Diet in Renal Disease trial; HOT, Hypertension Optimal Treatment trial; AASK, African-American Study of Kidney Disease.) (Adapted from Bakris et al [20])

   
UKPDS (<85mm Hg-Diastolic)
ABCD (<75mm Hg-Diastolic)
MDRD (<92mm Hg MAP)
HOT (<80mm Hg-Diastolic)
AASK (<92mm Hg MAP)
 
 
Number of antihypertensive drugs