Figure 1: Equations for CrCl and GFR estimation

CrCl (ml/min) by 24-hour urine collection (1)

= [UCr x 24-hr urine volume (ml/day)] / [SCr x 1440 (min/day)]

CrCl (ml/min) by Cockcroft & Gault formula (2)

= [(140 - Age) x Weight (kg) x 1.2 x 0.85 (if female)] / SCr

GFR (ml/min/1.73m2) by abbreviated MDRD equation (3)

= 186 x (SCr x 0.0113)-1.154 x Age-0.203 x 0.742 (if female) x 1.21 (if Afro-americans)

CrCl: creatinine clearance

UCr: urine creatinine concentration in mmol/L

SCr: serum creatinine concentration in mmol/L

MDRD: Modification of Diet in Renal Disease