| 1. |
Hepatectomy |
|
| - |
"gold standard" for cure |
|
|
| - |
surgical morbidity |
| - |
small proportion of HCC patients |
| - |
are surgical candidates |
|
| 2. |
Transplantation |
|
| - |
survival better than resection |
| - |
removes detectable and nondetectable tumours |
| - |
replaces the cirrhotic liver |
| - |
corrects portal hypertension |
|
|
| - |
donor shortage |
| - |
surgical morbidity |
| - |
life-long immunosuppression |
| - |
expensive |
|
| 3. |
Local ablation |
|
| - |
minimally invasive |
| - |
repeated sessions possible |
| - |
RFA has favourable short term results for
small HCC |
|
|
| - |
high incidence of local recurrence |
| - |
long term results lacking |
|
| 4. |
Intraarterial therapy |
|
| - |
safe |
| - |
minimally invasive |
| - |
2 RCTs showed survival benefit |
|
|
| - |
for palliation only |
| - |
variable response |
|